Minisymposium: Pathobiology of Liver Disease

Minisymposium: Pathobiology of Liver Disease

Tuesday, April 27, 2021 • 2:00 PM - 4:30 PM (EST)


Vik Meadows
Vik Meadows, MS, BS
Indiana University

Kari Nejak-Brown
Kari Nejak-Bowen, PhD
University of Pittsburgh


Session Description: Abstract-Driven Short Talks (15-minutes each)

  • Chair - Welcome and Introductions

Presentation Time

Presenting Author

Abstract Title

Abstract Number

2:00 - 2:15

Lindsey Kennedy

Secretin Treatment Promotes Hepatic Progenitor Cell Activation, Ductal-Canalicular Junction Formation and Amelioration of Liver Damage in a Model of Late-Stage Primary Biliary Cholangitis

Abstract R1679

2:15 - 2:30

Xiaojuan Chao

SQSTM1/p62 Inhibits whereas Nrf2 Promotes Tumorigenesis by Inducing Cell Population Remodeling and Metabolic Reprograming in Mouse Livers with mTORC1 Activation and Defective Autophagy

Abstract R1924

2:30 - 2:45

Hui Qian

Dual role of p62/SQSTM1 in acetaminophen-induced early acute injury and late recovery in mice

Abstract R2482

2:45 - 3:00

Gang Liu

Hepatic Autophagy Deficiency Leads to Increased Production of Extracellular Vesicles

Abstract R2600

3:00 - 3:15

Akanksha Sharma

Differential Effects of Endotoxin Lipopolysaccharide on Stellate Cells and Portal Fibroblasts: Implications in Fibrosis Originating in Central Versus Portal Injury

Abstract R4097

3:15 - 3:30

Vik Meadows

ASBT Vivo-Morpholino Decreases Hepatic Mast Cell, Fibrosis and Biliary Senescence in Mdr2-/- Mice

Abstract R3480

3:30 - 3:45

Adeola Michael

Investigating liver fibrosis in a humanized mice model of sickle cell disease

Abstract R4498

3:45 - 4:00

Matthew McMillin

Thrombospondin-1 Inhibition Reduces Nrf2 Activity and Increases Liver Injury during Acetaminophen-Induced Hepatotoxicity

Abstract R2127

4:00 - 4:15

Steve Mahanes

Increased hepatic JNK activation by ethanol is mediated by transcriptional suppression of mitogen-activated protein kinase phosphatase 1 (Mkp1): role of cAMP-specific protein kinase A

Abstract R3948

4:15 - 4:30

Evan Delgado

Diploid hepatocytes promote compensatory liver regeneration following acetaminophen induced acute liver injury

Abstract R4673

4:30 - 4:45

Jinqiang Zhang

EZH2 Drives Cholangiocarcinogenesis Through Downregulation of Tumor Suppressors Genes via Histone Methylation And microRNAs

Abstract R2196