Symposium: Fixing Fatty Liver

Symposium: Fixing Fatty Liver

Wednesday, April 28, 2021 • 2:00 PM - 5:00 PM (EST)

Sponsored by the ASIP Liver Pathobiology Scientific Interest Group


Kari Nejak-Bowen, MBA, PhDChair
Kari Nejak-Bowen, PhD
University of Pittsburgh

Session Description: In this session, we will approach the problem of non-alcoholic fatty liver disease (NAFLD) through improved understanding of the cellular and molecular mechanisms involved in disease progression. Recent advances in gut-liver axis, microbiome, and inflammation in the pathogenesis of NAFLD will be also discussed. Finally, we will explore novel signaling pathways that can be targeted for treatment of NAFLD.


  Chair - Welcome and Introductions  
2:00 PM - 2:30 PM Cholesterol and Bile Acid Metabolism in Fatty Liver Disease
Tiangang Li, PhD • University of Kansas Medical Center
Tiangang Li, PhD
2:30 PM - 3:00 PM Bile Acid Receptors and NAFLD
Huiping Zhou, PhD • Virginia Commonwealth University
Huiping Zhou, PhD
3:00 PM - 3:30 PM Gut Permeability in NASH: Role of Mucosal Immune Cells, Microbiota and Bile Acids
Reben Raeman, MS, PhD • University of Pittsburgh
Reben Raeman, MS, PhD
3:30 PM - 4:00 PM Novel Treatments for NAFLD
Naga P. Chalasani, MD • Indiana University
Naga P. Chalasani, MD
4:00 PM - 4:30 PM Inhibition of EGFR Receptor Prevents and Reverses Extreme NAFLD
George K. Michalopoulos, MD, PhD • University of Pittsburgh
George K. Michalopoulos, MD, PhD
4:30 PM - 5:00 PM Stress-responsive Gene FKBP5 Mediates Alcohol-induced Liver Injury Through the Hippo Pathway and CXCL1 Signaling
Suthat Liangpunsakul, MD • Indiana University
Suthat Liangpunsakul, MD
  Questions and Answers