Chair
William Muller, MD, PhD
Northwestern University
Session Description: Virtually all pathology involves inflammation, and inflammation requires a functioning vascular system. The interactions of leukocytes with cells and components of the vasculature are critical for the natural progression and resolution of inflammation. This session will start with a symposium highlighting some new developments in our understanding of the mechanisms that promote migration of leukocytes into inflamed tissue, and the consequences of those interactions for the promotion and regression of inflammation. This will be followed by an extended discussion involving audience members as well as the speakers to put these findings into context with each other and with other developments in the field. We hope that this conversation will elicit critical questions for future research.
We encourage attendees to submit questions for discussion in advance so that the panelists have time to provide thoughtful answers. Please send these questions to wamuller@northwestern.edu with the subject line “Inflammation Question.” The questions can be asked by the submitter at the meeting or anonymously, if desired.
| 2:00 PM - 2:30 PM | Mechanisms of Integrin Activation During Neutrophil Arrest Klaus Ley, MD • La Jolla Institute for Immunology |
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| 2:30 PM - 3:00 PM | Endothelial Cell Regulation of Transendothelial Migration: New Roles for Old Friends William Muller, MD, PhD • Northwestern University |
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| 3:00 PM - 3:30 PM | Neutrophil Reverse Transmigration: Mechanisms and Significance Sussan Nourshargh, PhD • University of London, London, United Kingdom |
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| 3:30 PM - 4:00 PM | Resolution of Inflammation in Atherosclerosis Ira Tabas, MD, PhD • Columbia University |
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| 4:00 PM - 5:00 PM | Panel Discussion with extensive audience participation |