VAMP Symposium: Immune Regulation of Barrier Forming Cells

VAMP Symposium: Immune Regulation of Barrier Forming Cells

Thursday, April 29, 2021 • 9:30 AM - 12:00 PM (EST)

Sponsored by the ASIP Vascular and Mucosal Pathobiology Scientific Interest Group


Jennifer Brazil, PhDChair
Jennifer Brazil, PhD
University of Michiga

Francis W. Luscinskas, PhDCo-Chair
Francis W. Luscinskas, PhD
Brigham & Women's Hospital

Session Description: Interactions at the immune-gastrointestinal epithelial interface are implicated in the chronic mucosal inflammation that is characteristic of inflammatory bowel disease. Immune cell intestinal epithelial interactions also play a critical role in the response to parasitic worms and during food induced anaphylactic reactions. Therefore, this symposium will highlight critical cellular and molecular interactions at the intestinal epithelial barrier under homeostasis and disease, discuss key steps that regulate the trafficking of neutrophils (key innate immune cells implicated in pathologic mucosal tissue damage) and detail how specialized epithelial cells (tuft cells) act as intestinal immune sentinels.


  Chair - Welcome and Introductions  
9:30 AM - 10:05 AM Type-2 Immunity at the Intestinal Epithelial Barrier
Simon Hogan, PhD • University of Michigan
Simon Hogan, PhD
10:05 AM - 10:40 AM Intermittent Rolling is a Striking Defect of the Neutrophil Extravasation Cascade Caused by Myosin1e Deficiency
Michael Schnoor, PhD • CINVESTAV, Mexico City, Mexico
Michael Schnoor, PhD
10:40 AM - 11:15 AM Intestinal Tuft Cells: Immune Sentinels and Effectors
Jakob von Moltke, PhD • University of Washington
Jakob von Moltke, PhD
11:15 AM - 11:30 AM Abstract R3672 – Gut Dysbiosis and Barrier Disruption are Associated with Diastolic Dysfunction in a Novel Mouse Model of Heart Failure with Preserved Ejection Fraction
Francisco J. Carrillo-Salinas, PhD • Tufts University
Francisco J. Carrillo-Salinas, PhD
11:30 AM - 11:45 AM Abstract R2096 – Insights into the Impact of Inflammatory Acidification on the Mucosa
Ian M. Cartwright, PhD • University of Colorado Anschutz Medical Campus
Jennifer Brazil, PhD
11:45 AM - 12:00 PM Abstract R2078 – Structural and Chemical Alterations to the Intestinal Mucus Barrier During Giardia duodenalis Infection
Elena Fekete, BSc • University of Calgary
Elena Fekete, BSc
  Questions and Answers