Symposium: The Gut Microbiota and Disease - Session I
Chair: Xiao-Ming Yin, MD, PhD • Tulane University 
Co-Chairs: Wenke Feng, PhD • University of Louisville
Maria Pilar Alcaide, PhD • Tufts University 
José Otero, MD, PhD • The Ohio State University

Session Description:  Humans carry a vast number of bacteria and other microbiota species from birth, and you may be more bacteria than you are you. An increasing importance of microbiota in human health and diseases has been recognized. Whatever your research subjects are, chances are that they may be influenced by the microbiota. This symposium will discuss the impact of gut microbiota on diseases ranging from neurodegeneration to diabetes, from the liver to the heart, and from the immune cells to the bone.

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Minisymposium: Pathobiology of Lung Disease
Chair: Piyali Dasgupta, PhD • Marshall University
Co-Chair: Sonika Patial, PhD, DVM, DACVP • Louisiana State University

Session Description: Abstract-Driven Short Talks (15-minutes each)

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Minisymposium: Mucosal Inflammation and Leukocyte Trafficking
Chair: Melinda Engevik, PhD • Medical University of South Carolina
Co-Chair: David Sullivan, PhD • Northwestern University

Session Description: Abstract-Driven Short Talks (15-minutes each)

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Career Conversations – Doing Business in Science
Sponsored by the ASIP Committee for Career Development and Diversity
Chair: Verónica Contreras-Shannon, PhD • St. Mary's University

Session Description: Every scientist is cut from a different mold! Join us for Doing Business in Science - a conversation with Drs. Bryan Brown and Cavan Bailey about their careers in Entrepreneurship/Start-Ups and Scientific Consulting, respectively. Both will provide insights about their career, their daily life, advice to trainees interested in a similar path, and answer your questions about their career journey. This is a great opportunity to learn about the many career possibilities available to you and to build your network! 

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Symposium: Single Cell Transcriptome and Epigenome Analysis, Using the Power of One to Interrogate Heterogeneity
Chair: Philip Iannaccone, MD, PhD • Northwestern University 
Co-Chairs: Qin Yan, PhD • Yale University 
David Williams, Jr., MD, PhD • University of North Carolina, Chapel Hill

Session Description: Recent advances in transcriptomics have shown that gene expression states vary tremendously from cell to cell. This variation is essential in development where the specification of fate depends on controlled heterogeneity. In cancer, genetic and epigenetic changes results in highly heterogeneous expression states despite clonal origins. This session will present the emerging single-cell technologies in transcriptomics and epigenomics, data analysis pipeline, and the biological significance of these data.

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Virtual Chat Lounge: ASIP Meet the ASIP Executive Officer
William B. Coleman, PhD • American Society for Investigative Pathology

Career Mentoring Session: Finding Your Path: Alternative Careers for Health Scientists
Chair: Jennifer Sanders, PhD • Rhode Island Hospital and Brown University
Co-Chairs: David Sullivan, PhD • Northwestern University
Marina Anastasiou, MSc • Tufts University

Session Description: This is the first session in a webinar series aiming to describe careers for MD/PhD or PhD-trained pathology scientists that fall outside the traditional professorship track. PhD scientists working in various fields and settings will share insights and give advice to trainees looking to explore alternative paths. With health scientists employed in various commercial settings from biotech companies to industrial operations and law and editorial services, a foundation in research can lead to unexpected and attractive career options. This session will be of interest to undergraduates, graduate/medical students, or post-doctoral fellows.

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Virtual Chat Lounge: ASIP Meet the marketing and Communications Manager
Gina LaBorde • American Society for Investigative Pathology

ASIP Highlights Session: I Am An ASIP Member and This Is My Science
Sponsored by the ASIP Committee for Career Development and Diversity
Chair: Edward A. Medina, MD, PhD • University of Texas Health Science Center
Co-Chairs: Titus A. Reaves, PhD • Medical University of South Carolina
Nakisha Rutledge, BSc • Northwestern University

Session Description: As a Society, we cannot escape the identity crisis we have confronted in the past - what is pathology and how do pathologists fit into the basic framework of biomedical science? This is an ongoing challenge that requires our members to educate others regarding the nature of the discipline of experimental pathology and how our research describes and investigates the pathology, pathogenesis, and pathophysiology of specific diseases at the molecular, cellular, organ, and organismal level. Overcoming this identity crisis requires effort on the part of each ASIP member and our success will be evident as we continue to attract bright and enthusiastic young investigators into the diverse field of experimental pathobiology.

The American Society for Investigative Pathology presents I Am An ASIP Member and This Is My Science a dynamic and inspiring session featuring ASIP Scientists on the Cutting Edge of Discovery briefly, present their research, accomplishments, career journeys, and service to ASIP. This session highlights the diversity among our membership, and provides trainees, young scientists, pathologists, and the members of the larger scientific community the opportunity to become inspired by Trailblazers in the field of investigative pathology.

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Young Scientist Leadership Award Lecture
Introduction - Satdarshan Paul Singh Monga, MD • University of Pittsburgh

Session Description: Dr. Preziosi will format her award lecture as a career development talk. She has always been passionate about helping earlier-stage trainees navigate their careers, and is hoping they can learn from her experiences. In the past few years her career has taken unexpected, but welcome, turns outside of her original career goals, and ASIP has been helping her every step of the way. Her talk will feature her experiences as a graduate student, postdoc, industry scientist, and now a life science consultant, and the advice and insight that she gathered at each stage. She hopes attendees will benefit from her talk regardless of their career stage and their current goals.

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Virtual Chat Lounge: ASIP Meet the AJP Team
Martha Furie, PhD • Stony Brook University
Emily Essex • American Society for Investigative Pathology

Minisymposium: Neuropathology
Chair: Christi Kolarcik, PhD • University of Pittsburgh
Co-Chair: Karam Soliman, PhD • Florida A&M University

Session Description: Abstract-Driven Short Talks (15-minutes each)

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Minisymposium: Pathobiology of Cancer
Chair: Douglas Stairs, PhD • Penn State College of Medicine
Co-Chair: Qing Zhang, PhD • UT Southwestern Medical School

Session Description: Abstract-Driven Short Talks (15-minutes each)

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Minisymposium: Pathobiology of Liver Disease
Chair: Vik Meadows, MS, BS • Indiana University
Co-Chair: Kari Nejak-Bowen, PhD • University of Pittsburgh

Session Description: Abstract-Driven Short Talks (15-minutes each)

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Symposium: Disease Modeling with iPSC: From Cells to Organoids
Chair: Philip M. Iannaccone, MD, PhD • Northwestern University 
Co-Chairs: Satdarshan Paul Singh Monga, MD • University of Pittsburgh 
Ivana Delalle, PhD, MD • Brown University

Session Description: The availability of human iPSC from various disease states presents an unprecedented opportunity to examine pathology and physiology in an intact tissue context. The decades since the early descriptions of stem cell derived “embryoid bodies”, the first example of “organoids”, have seen major advances in directed differentiation of stem cells and their organization into small structures mimicking normal organs. Organoids can be used to interrogate altered physiology and toxicology or as test beds for therapeutic intervention. Patient derived iPSC have been used to advance our understanding of many aspects of disease states. This session will highlight recent advances in both organoids and the use of directed differentiation of human iPSC in the study of disease.

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Symposium: The Gut Microbiota and Disease - Session II
Chair: Xiao-Ming Yin, MD, PhD • Tulane University 
Co-Chairs: Wenke Feng, PhD • University of Louisville
Maria Pilar Alcaide, PhD • Tufts University 
José Otero, MD, PhD • The Ohio State University

Session Description:  Humans carry a vast number of bacteria and other microbiota species from birth, and you may be more bacteria than you are you. An increasing importance of microbiota in human health and diseases has been recognized. Whatever your research subjects are, chances are that they may be influenced by the microbiota. This symposium will discuss the impact of gut microbiota on diseases ranging from neurodegeneration to diabetes, from the liver to the heart, and from the immune cells to the bone.

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Symposium: The "Ins" and "Outs" of Vascular Inflammation
Sponsored by the ASIP and the North American Vascular Biology Organization (NAVBO)
Chair: William Muller, MD, PhD • Northwestern University

Session Description: Virtually all pathology involves inflammation, and inflammation requires a functioning vascular system. The interactions of leukocytes with cells and components of the vasculature are critical for the natural progression and resolution of inflammation. This session will start with a symposium highlighting some new developments in our understanding of the mechanisms that promote migration of leukocytes into inflamed tissue, and the consequences of those interactions for the promotion and regression of inflammation. This will be followed by an extended discussion involving audience members as well as the speakers to put these findings into context with each other and with other developments in the field. We hope that this conversation will elicit critical questions for future research.

We encourage attendees to submit questions for discussion in advance so that the panelists have time to provide thoughtful answers.  Please send these questions to wamuller@northwestern.edu with the subject line “Inflammation Question.”  The questions can be asked by the submitter at the meeting or anonymously, if desired.

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Virtual Chat Lounge: ASIP Meet the Committee for Career Development and Diversity (CCDD) Chair
Edward Medina, MD, PhD • University of Texas Health Science Center

Virtual Chat Lounge: ASIP Meet the the Education Committee Chair
Elaine Bearer, MD, PhD • University of New Mexico Health Science Center

Rous-Whipple Award Lecture
Introduction - Xiongwei Zhu, PhD • Case Western Reserve University

Session Description: Dr. Perry will present the pathology of Alzheimer’s disease from the pathological perspective that places plaques and tangles as biological responses to metabolic and oxidative stress rather than the cause of disease. He will review his work demonstrating oxidative stress is the first abnormality of Alzheimer and that mitochondria, autophagy and metal redox chemistry are its source. In this mix, amyloid-ß reduced oxidative stress through Cu/Fe redox chemistry. This places the pathology as potentially protective, like inflammation, explaining why thirty years of focus and eventual success in removing pathology has not produced meaningful benefit for patients.

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Women in Pathology – Leadership Development Event – Part I
Co-Chairs: Maria Pilar Alcaide, PhD • Tufts University
Jennifer Sanders, PhD • Brown University
Nakisha Rutledge, BSc • Northwestern University
Francisco Carrillo-Salinas, PhD • Tufts University

Session Description: Confident leadership requires time and self-reflection about one’s current strengths, as well as areas for development. Putting energy and intention toward developing these areas can help us not only build our authentic leadership presence and voice, but also result in greater interpersonal effectiveness and impact. In this interactive 1-hour workshop with Leadership Coach Deb Elbaum, attendees will get clearer about their current leadership skills and identify where they can put attention to be even more successful in their current or future role.

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Career Conversations – Publish or Perish
Sponsored by the ASIP Committee for Career Development and Diversity
Chair: Marina Anastasiou, MSc • Tufts University

Session Description: Every scientist is cut from a different mold! Join us for Publish or Perish - a conversation with Drs. Chhavi Chauhan and Diane Bielenberg about their careers in Scientific Editing & Writing, and Academic Research & Teaching, respectively. Both will provide insights about their career, their daily life, advice to trainees interested in a similar path, and answer your questions about their career journey. This is a great opportunity to learn about the many career possibilities available to you and to build your network!

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Virtual Chat Lounge: ASIP Meet the Program Committee Chair
Jonathon Homeister, MD, PhD • University of North Carolina

Society of Toxicologic Pathology (STP) Symposium: Animal Models in Basic Research and Preclinical Science: The Critical Role of the Toxicologic Pathologist
Sponsored by the ASIP Environmental and Toxicologic Pathology Scientific Interest Group
Chair: Mark Hoenerhoff, DVM, PhD • University of Michigan
Co-Chair: Jack Harkema, PhD, DVM • Michigan State University

Session Description: Veterinary toxicologic pathologists play an integral role in biomedical and basic sciences, through translation of preclinical in vivo data for the study of human disease, development of new technologies and medical interventions, and drug development. Toxicologic pathologists also play a role in determination of chemical/drug adversity in animals and humans, and help predict relevance to humans taking into account mechanisms and margin of safety. Working with researchers, clinicians, and toxicologists, toxicologic pathologists can help facilitate a better understanding of disease processes through interpretation of animal models, drug development, and improve translatability of preclinical data in the “bench to bedside” approach to patient care.

Through expanding interdisciplinary collaborations with the human medical field and other disciplines, toxicologic pathologists are central to the “One Health” concept at the intersection of all aspects of health care for humans, animals, and environmental health. This session will showcase the role veterinary toxicologic pathologists play in basic research, investigative pathology, drug development, and imaging modalities to strengthen translatability of animal data to the clinic in collaboration with other scientists. This session will also highlight how toxicologic pathologists can inform on the validity, use, relevance, and power of animal models to study human disease.

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Symposium: The Great Debate - Fibrosis Across Organs: Triggers, Pathways, and Cellular Plasticity
Co-Sponsored by the ASIP and the American Society for Matrix Biology (ASMB)
Chair: Titus A. Reaves, PhD • Medical University of South Carolina
Co-Chair: Mangesh Kulkarni, PhD • University of Pittsburgh

Session Description: Fibrosing diseases are a broad spectrum of entities from organ-specific involvement to multi-system diseases with high morbidity and mortality and significantly unmet clinical needs. Progress in elucidating the pathogenesis of the fibroproliferative components across various diseases, including the critical roles of key cell types and the molecular mechanisms driving the transcriptional activation involved in the induction of fibrosis, has highlighted many new areas of therapeutic investigation and are currently underway. This session is designed to bring together translational biomedical researchers from a wide range of disciplines to discuss complex pathophysiologic mechanisms that underlie fibrosing diseases. You won’t want to miss the hot topic debate on Power Cell – Fibroblast or Macrophage that will follow the session talks.

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Breast Cancer Workshop - Tumor Microenvironment in Breast Cancer Progression
Sponsored by the ASIP Breast Cancer Scientific Interest Group
Chair: Bethany Hannafon, BS, PhD • University of Oklahoma Health Sciences Center
Co-Chair: Piyali Dasgupta, PhD • Marshall University

Session Description: This session will examine the role of the tumor microenvironment in primary breast cancer development to metastatic dissemination and therapeutic resistance. Attendees will hear from leaders in the breast cancer field about tumor-host crosstalk mediated by extracellular vesicles, the role of the immune microenvironment in cancer progression, tumor cell dormancy and its role in therapeutic resistance, and the role of the lymph node tumor microenvironment in the progression of lymph node breast cancer metastases.

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Virtual Chat Lounge: ASIP Meet the ASIP Executive Officer
William B. Coleman, PhD • American Society for Investigative Pathology

Blood Vessel Club™ Gut Microbiota in Vascular Disease
Sponsored by the ASIP Inflammation/Immunopathology Scientific Interest Group and the Vascular and Mucosal Pathobiology Scientific Interest Group
Chair: Jonathon W. Homeister, MD, PhD • University of North Carolina at Chapel Hill
Co-Chair: Denuja Karunakaran, PhD • The University of Queensland

Session Description:  This symposium explores the newest discoveries into the role the gut microbiome has in the pathobiology of vascular diseases. Presentations by national and international experts in the field will focus on the mechanisms by which the gut microbiome can modulate both atherosclerotic vascular disease and hypertensive vascular disease.

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Virtual Chat Lounge: ASIP Meet the Liver Pathobiology SIG Leaders
Satdarshan Paul Monga, MD • University of Pittsburgh
Kari Nejak-Bowen, PhD • University of Pittsburgh

Planning for Success: Navigating Your First Faculty Position
Sponsored by the ASIP Committee for Career Development and Diversity
Chair: Christi Kolarcik, PhD • University of Pittsburgh
Co-Chair: Traci Parry, PhD • University of North Carolina at Greensboro

Session Description:  Feeling overwhelmed as you wrangle your first faculty position? Come hear from our experienced faculty as they impart valuable advice and tactics on successfully planning, transitioning into, adapting, (and surviving!) your first years as a faculty member.

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Virtual Chat Lounge: ASIP Meet the President and President-Elect
Richard Mitchell, MD, PhD • Brigham & Women's Hospital
Patricia D’Amore, PhD • Schepens Eye Research Institute/Harvard Medical School

Virtual Chat Lounge: ASIP Meet the Breast Cancer SIG Leaders
Bethany Hannafon, PhD • University of Oklahoma
Dennis Jones, PhD • Boston University

Symposium: Fixing Fatty Liver
Sponsored by the ASIP Liver Pathobiology Scientific Interest Group
Chair: Kari Nejak-Bowen, PhD • University of Pittsburgh

Session Description:  In this session, we will approach the problem of non-alcoholic fatty liver disease (NAFLD) through improved understanding of the cellular and molecular mechanisms involved in disease progression. Recent advances in gut-liver axis, microbiome, and inflammation in the pathogenesis of NAFLD will be also discussed. Finally, we will explore novel signaling pathways that can be targeted for treatment of NAFLD.

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Symposium: Novel Regulators and Functions of Epithelial Junctions
Chair: Sean Colgan, PhD • University of Colorado
Co-Chair: William Muller, MD, PhD • Northwestern University

Session Description:  Epithelial junctions are key regulators of tissue integrity and homeostasis, and their compromise contributes to the pathogenesis of inflammatory and immune disorders. This symposium will highlight recent developments in this exciting area of research and will touch upon developmental and disease pathways. The talks will cover the role of intercellular junction proteins in a range of tissues, including simple and complex epithelia.

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Pathobiology Course for Research Scientists: Resolution of Inflammation
Sponsored by the ASIP Education Committee
Chair: Dipak Panigrahy, MD • Beth Israel Deaconess Medical Center/Harvard Medical School
Co-Chair: Alexander Sougiannis, PhD • Medical University of South Carolina

Session Description:  Unresolved inflammation is a major mechanism of pathogenesis in many human diseases. A paradigm shift is emerging in our understanding of the pathogenesis of inflammation which results not only from persistent activation of inflammatory signals, but also from the active loss of pro-resolution mechanisms. Differentiating between the suppression and resolution of inflammation driven by pro-resolution mediators is critical for the treatment of various inflammatory diseases.

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Symposium: Coagulation and Fibrinolytic Factors and Innate Immunity
Chair: Wendy Mars, PhD • University of Pittsburgh 
Co-Chair: Steven Gonias, MD, PhD • University of California, San Diego

Session Description:  Proteins involved in both the coagulation and fibrinolysis pathways do much more than their well-described historical roles affecting the formation and dissolution of clots. This session will highlight data from leaders in the field who are studying the function of hemostasis factors in innate immunity.

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Outstanding Investigator Award Lecture
Introduction - Abul Abbas, MBBS • University of California, San Francisco

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Club Hepatomania™ - Meet the Liver Experts - All Duct Up
Sponsored by the ASIP Liver Pathobiology Scientific Interest Group
Co-Chairs: Satdarshan Paul Singh Monga, MD • University of Pittsburgh
Kari Nejak-Bowen, PhD • University of Pittsburgh

Session Description:  The selected experts for this session possess broad expertise in cholangiocyte biology, cholangiopathologies, biliary fibrosis, liver development, and liver repair using experimental models.

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ASIP Town Hall Meeting
Chair: Richard Mitchell, MD, PhD • Brigham and Women’s Hospital
Co-Chairs: Patricia D’Amore, PhD • Schepens Eye Research Institute, Harvard Medical School
William B. Coleman, PhD • American Society for Investigative Pathology

Session Description:  Are you a new member of the ASIP and want to become more involved? Are you interested in working with the ASIP leadership and committees? Join us for open conversations and networking with the common goal of building a stronger ASIP.

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Virtual Chat Lounge: ASIP Meet the President and President-Elect
Richard Mitchell, MD, PhD • Brigham & Women's Hospital
Patricia D’Amore, PhD • Schepens Eye Research Institute/Harvard Medical School

Career Conversations – Innovation
Sponsored by the ASIP Committee for Career Development and Diversity
Chair: Verónica Contreras-Shannon, PhD • St. Mary's University

Session Description: Every scientist is cut from a different mold! Join us for Innovations - a conversation with Drs. Karthika Perumal and Robinna Lorenz about their careers in Patent Law and Biotechnology, respectively. Both will provide insights about their career, their daily life, advice to trainees interested in a similar path, and answer your questions about their career journey. This is a great opportunity to learn about the many career possibilities available to you and to build your network!

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Symposium: Mechanisms of Hepatic Turmorgenesis
Sponsored by the ASIP Liver Pathobiology Scientific Interest Group
Chair: Satdarshan Paul Singh Monga, MD • University of Pittsburgh 
Co-Chair: Heather Francis, PhD, FAASLD • Indiana University

Session Description: This symposium will provide up-to-date research (both clinical and translational) on liver cancer, specifically in hepatocellular and cholangiocarcinoma. Tumor phenotypes and signaling mechanisms will be discussed along with the role of the tumor microenvironment and cellular reprogramming. The overarching goals of this session are to provide a better understanding of the tumor microenvironment and cellular signaling events that regulate tumorigenesis in both hepatocellular and cholangiocarcinoma cancers, and to identify potential targetable components for treatment of liver cancers.

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VAMP Symposium: Immune Regulation of Barrier Forming Cells
Sponsored by the ASIP Vascular and Mucosal Pathobiology Scientific Interest Group
Chair: Jennifer Brazil, PhD • University of Michigan
Co-Chair: Francis W. Luscinskas, PhD • Brigham & Women's Hospital

Session Description: Interactions at the immune-gastrointestinal epithelial interface are implicated in the chronic mucosal inflammation that is characteristic of inflammatory bowel disease. Immune cell intestinal epithelial interactions also play a critical role in the response to parasitic worms and during food induced anaphylactic reactions. Therefore, this symposium will highlight critical cellular and molecular interactions at the intestinal epithelial barrier under homeostasis and disease, discuss key steps that regulate the trafficking of neutrophils (key innate immune cells implicated in pathologic mucosal tissue damage) and detail how specialized epithelial cells (tuft cells) act as intestinal immune sentinels.

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Virtual Chat Lounge: ASIP Meet the Gene Expression SIG Leaders
David Williams, MD, PhD • University of North Carolina
Qin Yan, PhD • Yale University School of Medicine
Philip Iannaccone, MD, PhD • Northwestern University

Symposium: Emerging Technologies From the Bench Disrupting Diagnosis and Care Near the Bedside
Sponsored by the ASIP Molecular Diagnostic Pathology Scientific Interest Group
Chair: D. Hunter Best, PhD • University of Utah
Co-Chair: Gregory Tsongalis, PhD • Dartmouth-Hitchcock Health System

Session Description:  This session will explore emerging genomic and molecular diagnostic tools that are being rapidly adopted in patient care, in the process transforming and disrupting the standard approach to clinical challenges as diverse as newborn diagnostics, microbiology, and oncology.

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Virtual Chat Lounge: ASIP Meet the ASIP Executive Officer
William B. Coleman, PhD • American Society for Investigative Pathology

HCS, ASIP, AAA Symposium: Geographic Information System (GIS) for Tissues and Tumors: Mapping Quantitative Data into an Anatomical Context
Sponsored by the ASIP, the Histochemical Society, and the American Association for Anatomy
Chair: Paul Goodwin, PhD • Cytiva

Session Description: Histochemistry is the science of identifying biomolecules in context of biological structures. The science is moving from qualitative and descriptive to quantitative and precise. Moreover, adjacent tools have been established that provide quantitative data but lack the structural context (-omics). For example, we can identify and enumerate immune cells but we struggle with quantitative descriptors of their place relative to important anatomical structures such as blood vessels, extracellular matrix, and even other cells. This session brings together speakers to talk about data analytics in context of geospatial descriptors and biologists (anatomists, pathologists, physiologists, etc.) who are working with spatial mapping of quantitative data within biological systems.

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The Journal of Histochemistry & Cytochemistry Lecture
Chair: Stephen Hewitt, MD, PhD • Editor, Journal of Histochemistry and Cytochemistry • National Cancer Institute/National Institutes of Health

Session Description: Over 53% of PhDs are awarded to women. Yet, only 12% of recognized innovators in the United States are women.  Women and diverse employees have technical skill and knowledge, yet their contributions are not patented at the same rate as those of their male counterparts. These statistics suggest that our organizations may not be capturing the full contribution of a large segment of our technical workforce – resulting in significant lost opportunity costs (e.g., unpatented inventions, delayed disclosures, etc.)  The insights and perspectives of women are necessary to solve the monumental challenges our organizations face. Join HCS and the Journal of Histochemistry & Cytochemistry as we explore what is needed to help organizations move the needle on achieving gender parity in innovation.

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Minisymposium: Endothelial Cells in Immunity and Cardiovascular Disease
Chair: Maria Pilar Alcaide, PhD • Tufts University
Co-Chair: Kathryn Hendee, PhD • Medical College of Wisconsin

Session Description: Abstract-Driven Short Talks (15-minutes each)

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Presidential Symposium: Second Chapters: Careers in Academia After a Life in the Lab
Chair: Richard N. Mitchell, MD, PhD • Brigham and Women’s Hospital and Harvard Medical School

Session Description: Hard-wired into the ASIP Mission Statement is the promotion of the “discovery, advancement, and dissemination of basic and translational knowledge in experimental pathology and related disciplines.” This is achieved by many of the ASIP membership through their research pursuits—and the associated publications and meeting presentations. However, ASIP has an equally important responsibility (also highlighted in the Mission Statement) in “disseminating knowledge…and fostering educational activities”…across the spectrum from undergraduates to industry, and from politicians to emeritus professors.

Indeed, Ramzi Cotran always strongly believed that one couldn’t be a good pathologist and investigator without being a stellar educator. It’s equally important to emphasize that sharing our discoveries requires a robust editorial process, and couldn’t be accomplished without a solid and enlightened ASIP leadership in support of the Society and its meetings. Consequently, the goal of the ASIP President’s Symposium at EB2021 is to spotlight the administrative, editorial, and educational roles played by ASIP members, and share the trials and tribulations—and the satisfaction—that can come from contributing to the core ASIP mission in ways outside of the laboratory.

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Symposium: Deep Learning and Artificial Intelligence in Pathology
Chair: Stanley Cohen, MD • Rutgers-New Jersey Medical School
Co-Chair: John Tomaszewski, MD • University at Buffalo

Session Description: The use of artificial intelligence has become ubiquitous in many aspects of human endeavor including medicine. In particular, Pathology is well-positioned to take advantage of this methodology both because of our heavy reliance on large amounts of laboratory data and the need for high level image interpretation. This session will begin with an overview of the underlying mechanisms of artificial intelligence and deep learning, followed by examples of the implementation of AI in solving problems such as tumor grading, interactions between tumors and the host’s immune response, with the ultimate aim of prognostic prediction. The session will conclude with progress in the fusion of multiple pathology data streams via AI-based strategies.

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ASIP Business Meeting and Awards Presentations
Chair: Richard N. Mitchell, MD, PhD • Brigham and Women’s Hospital and Harvard Medical School

Session Description: During this session, members will hear reports from the President, Secretary Treasurer, and other members of the ASIP Council (Committee Chairs) with respect to the state of Society operations, programs, and finances. In addition, the 2021 meritorious awards will be presented, and Trainee and Young Faculty Scholar Awardees will be recognized. The event will conclude with the ceremonial passing of the gavel to the President of the Society.

Women in Pathology – Leadership Development Event – Part II
Co-Chairs: Maria Pilar Alcaide, PhD • Tufts University
Jennifer Sanders, PhD • Brown University
Nakisha Rutledge, BSc • Northwestern University
Francisco Carrillo-Salinas, PhD • Tufts University

Session Description: The mission of the Women in Pathology Session 2 at EB 2021 is to build upon what is learned in Session 1 about confident leadership. Attendees will engage in conversations focused on the following topics, and discuss how these sessions have contributed to shape their confidence, and career paths.

• Resilience and wellness
• Managing your inner critic
• Active listening and difficult conversation
• Vision and setting boundaries

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Career Conversations – Government and Science Policy
Sponsored by the ASIP Committee for Career Development and Diversity
Chair: Daisy Shu, PhD • Schepens Eye Research Institute

Session Description: Every scientist is cut from a different mold! Join us for Government and Policy - a conversation with Drs. Yvette Seger and William Stetler-Stevenson about their careers in Public Policy and Research in Government, respectively. Both will provide insights about their career, their daily life, advice to trainees interested in a similar path, and answer your questions about their career journey. This is a great opportunity to learn about the many career possibilities available to you and to build your network!

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Symposium: Drinking from the Firehose: Progress in the Practical Uses of Big Data
Chair: Dan Milner, Jr., MD, MSc, FASCP • American Society for Clinical Pathology
Co-Chair: Kevin Gardner, MD, PhD • Columbia University Medical Center

Session Description: Human diagnostic medicine has always been fed by the vast array of research from the bench but with considerable lag from first discovery to clinical use. The advent of advance information technology, increasing computational capacity, and enormous data per patient has hastened research efforts. Translation into immediate, practical clinical applications occur constantly, creating a flooding river of data acquisition, analysis, and interpretation. In this session, four leaders at the forefront of their fields will discuss specific examples of big data and the immediate and future impacts on human health. From the areas of transfusion medicine, digital pathology, informatics, and immunomics, the flood of science and data will be presented through the lens of complex yet practical big data projects and explain how to prepare for and benefit from them in both the research laboratory and the clinical sphere.

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ACVP-ASIP Symposium: Comparative Hemostasis and Thrombosis
Sponsored by the ASIP Veterinary and Comparative Pathology Scientific Interest Group and the American College of Veterinary Pathologists (ACVP)
Chair: Nora L. Springer, DVM, DACVP • Kansas State University College
Co-Chair: Katherine N. Gibson-Corley, DVM, PhD, DACVP • University of Iowa

Session Description:  Veterinary scientists discuss cutting edge research in canine hemostasis and thrombosis and correlate to the equivalent human disease.

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XX^th Annual Workshop in Graduate Education in Pathology: Training and Fellowship Grants
Sponsored by the ASIP Education Committee
Chair: Titus A. Reaves, PhD • Medical University of South
Co-Chair: José Otero, MD, PhD • The Ohio State University

Session Description: This session will focus on everything the prospective grantee needs to know about training grants (T’s, and F’s) that score and get funded. The information presented will be invaluable as the grant environment is a constantly evolving. Preparation is essential to overcome the challenges facing grant writers coupled with being knowledgeable on the types of training grants that are best for your individual situation. The speaker, Dr. McManus has extensive experience as she has been a PI for a number of years, and has had success in writing and obtaining all types of grants. Attendees will understand the current state of the industry and the information presented will assist the grant writer to enter and stay at the forefront of the process. The session concludes with Dr. Jackie Bader, an early career researcher, who was successful in obtaining two of these training grants.

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Virtual Chat Lounge: ASIP Meet the ASIP Executive Officer
William B. Coleman, PhD • American Society for Investigative Pathology

Symposium: Precision Oncology: The Promise for Translating Personal Genomics into Clinical Action
Chair: Kevin Gardner, MD, PhD • Columbia University Medical Center
Co-Chair: Elizabeth Whitley, DVM, PhD • MD Anderson Cancer Center

Session Description: Tapping into the vast amount of information stored in the genome holds great promise for the development of targeted, patient-specific clinical decision-making. In this symposium, we highlight several vanguard studies that support developing knowledge-based therapeutics and preventions for cancer. The first presentation of this symposium will focus on the use of genomic technologies and bioinformatics analysis to determine relationships between germ-line and somatic alterations in populations and cancer risk and progression. The second presentation will delve into hereditary differences in Vitamin D metabolism and prostate cancer aggressiveness and mortality. The third presentation will describe genetic and environmental factors among Latina women that affect the risk of developing breast cancer or of having progressive disease.

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Cotran Early Career Investigator Award Lecture
Introduction - Satdarshan Paul Singh Monga, MD • University of Pittsburgh

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Virtual Chat Lounge: ASIP Meet the Research and Science Policy (RSPC) Chair
Kelsey McKillip, PhD • University of Cincinnati

Mentoring Workshop: The ABCs of the IDP
Sponsored by the ASIP Education Committee and the ASIP Committee for Career Development and Diversity
Chair: Roberto I. Mota Alvidrez, MD • University of Pittsburgh
Co-Chair: Christi Kolarcik, PhD • University of Pittsburgh

Session Description: This session will showcase the ability of a successful and efficient IDP in eliminating difficult conversations in mentor-mentee interactions. Our speakers will highlight the importance of writing a successful IDP throughout your scientific career. The workshop will face out difficult scientific scenarios in which having a well outlined IDP is beneficial in all stages of scientific career.

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Virtual Chat Lounge: ASIP Meet the Vascular and Mucosal Pathobiology (VAMP) SIG Leaders
Asma Nusrat, MD • University of Michigan
David Sullivan, PhD • Northwestern University
Michael Schnoor, PhD • Centro de Investigacion y de Estudios Avanzados (CINVESTAV)
Dan Milner, MD MSc(Epi) MBA • American Society for Clinical Pathology
Bill Luscinskas, PhD • Brigham & Women's Hospital

Minisymposium: Tissue Barriers and Intercellular Junctions
Chair: Andrei Ivanov, PhD • Cleveland Clinic Foundation
Co-Chair: Kris Chadee, PhD • University of Calgary

Session Description: Abstract-Driven Short Talks (15-minutes each)

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Minisymposium: Novel Insights into Cardiac Function and Myocardial Response to Injury
Chair: Traci Parry, PhD • University of North Carolina at Greensboro
Co-Chair: Jonathon Homeister, PhD • University of North Carolina, Chapel Hill

Session Description: Abstract-Driven Short Talks (15-minutes each)

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SCVP-ASIP Joint Symposium: Clonal Hematopoiesis: Impact on Inflammation and Cardiovascular Disease - Cardiac Pathology
Sponsored by the ASIP Inflammation/Immunopathology Scientific Interest Group and the Society for Cardiovascular Pathology (SCVP)
Chair: James Stone, MD, PhD • Massachusetts General Hospital

Session Description: The acquisition of aberrant clonal cell populations within the bone marrow has been observed during aging. It is now becoming clear that such clonal hematopoiesis may play important roles in age-related diseases, particularly inflammatory and age-related diseases of the cardiovascular system such as atherosclerosis. This session will involve leaders in the field sharing their insights into this new and evolving area of disease-related research.

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SIPMeT Symposium: Epigenetic Regulation and Cancer
Sponsored by ASIP and the Società Italiana di Patologia e Medicina Traslazionale/Italian Society of Pathology and Translational Medicine (SIPMeT)
Co-Sponsored by the ASIP Gene Regulation Scientific Interest Group
Chair: Massimiliano Corsi Romanelli, PhD, MD • University of Milan, Milan Italy
Co-Chair: Francesco Curcio, MD • University of Udine, Udine, Italy

Session Description: In this session, we will explore the role of epigenetic regulation in cancer development and therapy. The talks will include new and innovative methodologies, molecular studies, and novel targets for treatment.

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Expert Roundtable: Toward Understanding and Containing the COVID-19 Pandemic
Chair: Chhavi Chauhan, PhD • American Society for Investigative Pathology

Session Description: This session will touch upon numerous dimensions of understanding and containing the ongoing global pandemic. This timely session is structured for various experts to present short lightening talks sharing updates on mechanisms underlying COVID-19 infections and its pathogenesis as well as exploring and predicting outcomes based on underlying co-morbidities. The experts will also share updates on the current and emerging treatments for containing the global COVID-19 pandemic. The lightening talks will be followed by a live moderated Q&A session based on audience questions. This session will appeal to researchers, clinicians, companies developing COVID-19 surveillance, management, and treatment products, as well as the caregivers and lay public.

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